Tuesday, February 10, 2009

Cell-CT, a 3-D Single Cell Microscopy Might Become a New Tool for Cancer Diagnosis

Filed under: Genetics

Researchers at VisionGate, a Seattle, WA company, with the help of scientists at the University of Washington developed a new three dimensional microscope that uses light to scan individual cells from all angles. Similar to a CT scanner, the device rotates a cell encased in a gel in front of a microscope. Using proprietary software, the device reconstructs volumetric structures within cells, such as chromosomes, and these can be used as markers for cancer and other conditions.

After the jump, check out a video of a cell that belongs to a the muntjac deer species. Its six chromosomes have been colored with a fluorescent dye. The resolution of the image is 0.35 micrometers - about three times better than that of the 2-D images currently used for cancer diagnoses.

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