Monday, September 29, 2008

Guess-A-Nobel Contest

Filed under: Medgadget Exclusive

In one week from today, the Nobel Foundation will start announcing this year's Nobel Prizes. Medgadget is proud to present the first ever Guess-A-Nobel contest. Here's your chance to shine: name either the scientist(s) or discoveries in the comments to this post, and win one of the new iPod nanos.

Since we are a medical blog, initially we were thinking only about the Nobel Prize in Physiology or Medicine. But then we decided to expand to include the other two supreme sciences of nature: Physics and Chemistry.

So here are the rules:

1. Anyone can enter by writing a comment to this post. Please make sure you leave your email address, so we can get in touch with you.

2. Identify either the scientist(s) or discoveries in Medicine, and/or Physics and/or Chemistry, for your chance to win an iPod nano, or even three of them.

3. If a winner lives outside the US, Canada, or EU, instead of sending the prize, we'll transfer an equivalent amount of ca$h via a PayPal account.

4. Deadline for entries is Midnight Pacific Standard Time on Saturday Oct. 4.

Good luck to all!

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replies: 69 comments
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My first bet and the last for Medical Nobel:

Use of Stem cell simulation for organ / tissue / nerve regrowth should make it to the Nobel prize this year.

With so many new techniques and radically different approach to the technique, clearly the one involving minimal bio-chemical manipulation will be the best, however, ones that induce cell differentiation under environmental control seems likely to be the winner.

May the best technique win the Nobel.


Posted by:
on September 28, 2008 10:51 PM GMT

For medicine: Robert Langer, for his work in drug delivery and tissue engineering
For chemistry: George Whitesides, for his work in surface and physical chemistry


Posted by:
on September 29, 2008 04:55 AM GMT

For Medicine

Jules Hoffmann, S. Akira and Ruslan Medzhitov for their discovery and work of Toll-like receptors and contributions to the field of Innate Immunity.


Posted by: Luis
on September 29, 2008 05:35 AM GMT

For Medicine:James Till and Ernest McCulloch

For Chemistry:George Whitesides

For Physics : Hawking , Witten


Posted by: Ram
on September 29, 2008 06:21 AM GMT

For Medicine: Dr. Brian Druker at Oregon Health Sciences University for development of the cancer drug Gleevec


Posted by: Jim
on September 29, 2008 06:43 AM GMT

Chemistry - John Pople - computational methods in quantom chemistry
Gotta represent the uni


Posted by: Byron
on September 29, 2008 08:07 AM GMT

The Steitz's

Joan Steitz for her contributions detailing snRNP functions
Tom Steitz for the structure of possibly the largest RNP, the ribosome


Posted by: benUSES
on September 29, 2008 09:29 AM GMT

Medicine: Stan Fields for yeast two-hybrid protein interaction screen
Chemistry: Ken Houk for computational bio-design


Posted by: 33
on September 29, 2008 09:40 AM GMT

(1) Physiology or Medicine (Oct 6)

Alfred Knudson (Fox Chase) and Robert Weinberg (MIT) for their original contribution to the discovery of tumor suppressor genes (esp. RB, the retinoblastoma gene).

(2) Physics (Oct 7)

Adam Riess (Johns Hopkins) and Saul Perlmutter (Berkeley) for their discovery of dark energy.

(3) Chemistry (Oct 8)

Roger Tsien for his invention of Calcium Dye and Douglas Prasher for his invention of Green Fluorescent Protein (GFP) to study signal transduction activities in live cells. Marty Chalfie (Columbia) has a long shot for the third spot because his contributions to the GFP technology are also well documented.


Posted by: Omni
on September 29, 2008 09:42 AM GMT

Jack Szostak .- First yeast artificial chromosome, recombination mechanisms,
in vitro selection to study the evolution of catalytic RNAs ( ribozymes)


Posted by: Brian Hauge
on September 29, 2008 10:22 AM GMT

Probably for Chemistry (but maybe Medicine or Physiology) Leroy Hood


Posted by: Patrick L Coleman
on September 29, 2008 10:51 AM GMT

my guess is Dr. Willam Kolff who is considered the inventor of the artificial kidney.


Posted by: Mike Gentry
on September 29, 2008 10:53 AM GMT

In Physiology or Medicine, Kazutoshi Takahashi and Shinya Yamanaka for development of pluripotent stem cells from somatic tissue using defined transcription factors.


Posted by: Mark Samuels
on September 29, 2008 10:59 AM GMT

Ptashne or Brent. for any of various accomplishments.


Posted by: DJ
on September 29, 2008 11:57 AM GMT

Physiology or Medicine:Enabling the Human Genome Project - Leroy Hood for the automated sequencer and Melvin Simon for the Bacterial Artificial Chromosome the technique that provided the samples that were sued in the sequencer.

Chemistry: (someone partially beat me to this prediction) - Roger Tsien, Martin Chalfie (rather than Doug Prasher) and Tulle Hazelrigg for the innovation of fluorescent tags to monitor proteins


Posted by: Madhu
on September 29, 2008 12:56 PM GMT

Tom Steitz for ribosome crystal structure


Posted by: Jim Reilly
on September 29, 2008 01:04 PM GMT

2008 Nobel prize for
Medicine & Physiology: Evans/Jensen/Chambon for nuclear hormone receptors
Chemistry: Rothman/Schekman for membrane vesicle fusion/transport


Posted by: Manu Sharma
on September 29, 2008 05:24 PM GMT

OCT 6 Prize for Physiology & Medicine

Prof Elizabeth Blackburn for her groundbreaking work in telomeric DNA


Posted by: Sonya P
on September 29, 2008 08:57 PM GMT

Chemistry: Sir J. Fraser Stoddart for his work on Supramolecular Chemistry and Nanotechnology


Posted by: JZ
on September 30, 2008 08:31 AM GMT

Chemistry: ROGER Y. TSIEN, --florescent protein probes
Physics: Vera C. Rubin -- Dark Matter
Medicine: Akira, Hoffman, and Beutler -- toll-like receptors and innate immunity


Posted by: Peter
on September 30, 2008 08:47 AM GMT

Chemistry: Karplus - Contributions to quantum chemistry, NMR spectroscopy, and molecular dynamics simulations of biological macromolecules (to name a few)

Medicine: Ventner/Collins/Lander - Human Genome project


Posted by: Bryan
on September 30, 2008 09:09 AM GMT

My guess is John Altman, McHeyzer-Williams, and Mark Davis for the invention of MHC tetramers. (Physiology or Medicine)

To the comment about tumor suppressor genes, I would include Burt Volgelstein at Johns Hopkins University in addition to Weinberg and Knudson.


Posted by: CHM
on September 30, 2008 09:35 AM GMT

Chemistry or Physiology

Stuart Schreiber and Gerald Crabtree for discovery of small-molecule dimerizers, which provide small-molecule activation over numerous signaling molecules and pathways through proximity effects


Posted by: ranell
on September 30, 2008 01:12 PM GMT

Medicine: Fred Gage (possibly with Elizabeth Gould) - characterization of adult neurogenesis and adult neural stem cells


Posted by: JA
on September 30, 2008 02:38 PM GMT

Medicine - James Till and Ernest McCulloch

Chemistry - George Whitesides


Posted by: abhi
on September 30, 2008 02:57 PM GMT

Medicine: Irv Weissman for his work on hematopoeitic stem cells.


Posted by: dsj
on September 30, 2008 03:30 PM GMT

Physics - Nick Holonyyak for the LED.


Posted by: illini
on September 30, 2008 05:16 PM GMT

Medicine: Gary Ruvkun and Victor Ambros for the discovery of the first microRNA lin-4


Posted by: Liz
on September 30, 2008 06:41 PM GMT

(1) Chemistry

George Whitesides
Sir J. Fraser Stoddart

(2) Physics

S. Iijima

(3) Physiology or Medicine

Roger Tsien
Robert Weinberg
Jack Szostak


Posted by: hui WEI
on October 1, 2008 02:45 AM GMT

Physics: Atsuto Suzuki & Art MacDonald
Chemistry: Fraser Stoddart & Jean-Pierre Sauvage
Medicine: Leroy Hood


Posted by: SJC
on October 1, 2008 07:39 AM GMT

I would not be surprised if Dean Kamen wins a Nobel Prize in Medicine for his work with prosthetic limbs.


Posted by: mlshimr
on October 1, 2008 09:13 AM GMT

Nobel Prize in Chemistry: Three of the following Osamu Shimomura; Roger Tsien; Marty Chalfie; Sergey Lukyanov or Doug Prasher


Posted by: Marc Zimmer
on October 1, 2008 11:27 AM GMT

For Medicine, I think the prize will go to Brian Druker of Oregon Health & Science University for his work in developing the molecularly targeted cancer therapy Gleevec, as this has really validated and revolutionized the approach and aim to designing novel cancer therapies.


Posted by: Chris
on October 1, 2008 11:46 AM GMT

Physiology or Medicine: One or two of the following: Joan Massagué, Bob Weinberg, Bert Vogelstein, Gerard Evans


Posted by: Lars
on October 1, 2008 12:35 PM GMT

Physiology or Medicine: Tony Pawson for discovery of the SH2 domain and other domains


Posted by: Karl
on October 1, 2008 12:37 PM GMT

Medicine - Janet Rowley for her work in chromosomal translocations in leukemia and cancer.


Posted by: CY
on October 1, 2008 01:54 PM GMT

For Chemistry: George Whitesides, Allen Bard


Posted by: JLG
on October 1, 2008 02:14 PM GMT

Physiology/Medicine:

Elizabeth Blackburn and Carol Greider for the discovery of telomerase


Physics:

Yoichiro Nambu for his contributions to the theory of symmetry breaking and/or QCD
Makoto Kobayashi and Toshihide Maskawa for introducing 3rd generation of quarks to explain CP violation


Chemistry:

Harry Noller, Thomas Steitz, and Peter Moore for their work on ribosome structure


Posted by: HI
on October 1, 2008 04:39 PM GMT

Chemistry: George Whitesides


Posted by: AdamK
on October 1, 2008 11:36 PM GMT

Medicine: Miguel Nicolelis for his work on
brain-machine interface and brain-computer interface.


Posted by: Daniel Martins
on October 2, 2008 08:14 PM GMT

Medicine:
Dr. Michael Phelps for development of PET scanning.


Posted by: HZ
on October 2, 2008 08:14 PM GMT

CHEMISTRY: Prof. M.J. Krische for his work on "Hydrogen mediated c-c bond formation"


Posted by: Santosh Kumar Gurung, From S. Korea
on October 2, 2008 09:33 PM GMT

Chemistry: Fritz Vögtle, Jean Fréchet and Donald Tomalia for the development of dendrimers.


Posted by: RMR
on October 3, 2008 01:54 AM GMT

I gotta represent theory, so Martin Karplus and Eric Heller for Chemistry.


Posted by: TheMatt
on October 3, 2008 06:43 AM GMT

Medicine: Miguel Nicolelis, for his work on brain-computer interfaces.


Posted by: Luciana Christante
on October 3, 2008 02:01 PM GMT

Medicine: Shizuo Akira, Bruce A. Beutler, Jules A. Hoffman

Physics: Andre K. Geim, F.R.S., Kostya Novoselov

Chemistry: Charles M. Lieber


Posted by: MikeP
on October 3, 2008 02:38 PM GMT

Medicine: David Julius and Baruch Minke

Chemistry: Charles Lieber and Roger Tsien

Physics, Andre Geim., Kostya Novoselov and Vera Rubin


Posted by: David
on October 3, 2008 08:04 PM GMT

Medicine: Joan Massagué. For his discoveries about the role of microRNAs in cancer.
Chemistry: Frances H. Arnold and Manfred T. Reetz for their contribution to Directed Enzyme Evolution, that opened a new era in chemical catalysis.


Posted by: CR
on October 3, 2008 08:47 PM GMT

Physiology and Medicine: Ruvkun and Ambros for discovery and mechanisms of microRNA gene regulation.

Chemistry: Tsien and Prasher for fluorescent proteins.


Posted by: AS
on October 4, 2008 10:52 AM GMT

Medicine: Victor Ambros and Gary Ruvkun for the microRNAs lin-4 and let-7

Second Guess (Medicine): Elizabeth Blackburn, Carol Greider, and Jack Szostak for telomeres and telomerase.

Chemistry: Tom Steitz and Harry Noller for the ribosome structure.


Posted by: Christopher Hammell
on October 4, 2008 11:02 AM GMT

Physiology or Medicine

Pierre Chambon, Ronald Evans, and Elwood Jensen

"For their discovery of the nuclear hormone receptor superfamily"


Posted by: Josh Lacsina
on October 4, 2008 05:03 PM GMT

For Chemistry: George Whitesides

"For his pioneering work in nanotechnology and surface science"


Posted by: JMC
on October 4, 2008 07:39 PM GMT

Please, no more nominations.


Posted by: DrO
on October 5, 2008 08:58 AM GMT

Chemistry: Suzuki, Heck for development of Pd catalysis


Posted by:
on October 6, 2008 08:59 AM GMT

Tsien for fluorescent probes. aka Calcium dyes AND GFP. Only way to resolve the Shimomura, Prasher, Chalfie, Tsien musical chairs problem.

Lukyanov is way, way, way late to the party.


Posted by:
on October 7, 2008 05:14 PM GMT

Chemistry: Willson, Frechet and Ito for chemically amplified photoresists.


Posted by: Mike
on October 7, 2008 06:00 PM GMT

Gotta second this:
Physics: Atsuto Suzuki & Art MacDonald

It'll happen eventually. Bonus points: I get bragging rights for being on SNO.


Posted by: Nathaniel
on September 28, 2009 12:03 PM GMT

Chemistry: George Whitesides
Medicine: James Till


Posted by: Jason Connelly
on September 28, 2009 12:10 PM GMT

I think the Green Fluorescent Protein by Douglas Prasher is a solid bet chemistry wise.


Posted by: Antonio Amorelli
on September 28, 2009 12:21 PM GMT

It's a long shot, but I think Robert May should win, for his work on complex population dynamics and epidemiology.


Posted by: Eric Pedersen
on September 28, 2009 12:33 PM GMT

For Chemistry: Gerald Joyce, of Scripps


Posted by: Susan
on September 28, 2009 12:40 PM GMT

Physics: Mikheyev, Smirnov, and Wolfenstein


Posted by: JQD
on September 28, 2009 12:40 PM GMT

Enter me in the contest!

I think Stephen Hawkins will for physics.


Posted by: darth_borehd
on September 28, 2009 01:03 PM GMT

chemistry: Arieh Warshel: computational chemistry and biophysics: protein function


Posted by: n.a.
on September 28, 2009 01:04 PM GMT

Arnold Levine, for p53.


Posted by: Frank
on September 28, 2009 01:19 PM GMT

Physics :
Aharonov and Berry

Chemistry :
Whitesides


Posted by: Mithun
on September 28, 2009 01:21 PM GMT

Nobel Prize for Physiology and Medicine: Elizabeth Blackburn, Carol Greider and Jack Szostak for work on telomerase


Posted by: BrentH
on September 28, 2009 02:04 PM GMT

Vera C. Rubin rocks on physic


Posted by: zerocold
on September 30, 2009 01:28 PM GMT

Please enter my predictions in the Guess-A-Nobel Contest.

PHYSIOLOGY OR MEDICINE: Elizabeth H. Blackburn

PHYSICS: Peter Zoller

CHEMISTRY: Michael Gratzel


Posted by: Robby Maddin
on October 1, 2009 12:36 AM GMT

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