Tuesday, January 22, 2008

Novel Dark-field X-ray Technology Developed

Filed under: Radiology

Swiss scientists have developed a method to create dark-field x-ray images using the same wavelengths as those in standard contemporary x-ray machines.

Unlike traditional x-ray images, which show a simple absorption contrast, dark-field images capture the scattering of the radiation within the material itself, exposing subtle inner changes in bone, soft tissue, or alloys. The overall clarity of the images is striking. The improved sensitivity in measuring bone density and hairline fractures could help diagnose the onset of osteoporosis. Because cancer or plaque cells scatter radiation slightly differently than normal cells, dark-field x-ray images can also be used to explore soft tissue, providing safer early diagnosis of breast cancer or the plaques associated with Alzheimer’s disease.

Security screening equipment equipped with dark-field image capability could better identify explosives, whose micro-crystalline structures strongly scatter x-ray radiation. And because x-rays penetrate a material without damaging it, dark-field images could help reveal scattering-producing micro-cracks and corrosion in structures such as airplane wings or the hulls of boats.

“Researchers have been working on dark-field x-ray images for many years,” explains Franz Pfeiffer, a professor at EPFL and researcher at the PSI. “Up until now these images have only been possible using sophisticated crystal optical elements.” Crystal optics, however, only work for a single x-ray wavelength and thus are highly inefficient. “Our new technique uses novel x-ray optical components, in the form of nanostructured gratings, that permit the use of a broad energy spectrum, including the standard range of energies in traditional x-ray equipment used in hospitals or airports,” adds Christian David, Pfeiffer’s colleague at PSI. “This opens up the possibility for adapting current imaging equipment to include dark-field imaging.”

Pfeiffer plans to collaborate with the Center for Biomedical Imaging (CIBM), a joint center with the Universities of Lausanne and Geneva and their associated hospitals, to develop an adaptation for existing medical equipment.

Press release: New technology sharpens X-ray vision ...

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